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International Journal of Gastroenterology Research

Vol. 6, Issue 1, Part A (2024)

Prescription trends in the management of gastro-esophageal reflux disease (GERD) in India


Manjula S and Krishna Kumar M


Background: Gastroesophageal reflux disease (GERD) is one of the most common diseases seen in many countries for which majority of the population prefer proton pump inhibitors (PPI) and histamine-2 (H2) blockers along with medications like non-steroidal anti-inflammatory drugs (NSAIDs) and other drugs. Concerns have been raised about the prescription of these drugs as they are often prescribed without clear indications. Prescribing pattern should be evaluated periodically to promote rational use of medicine. Moreover, an understanding of the appropriate treatment plan for GERD based on the patient’s condition is essential for practitioners across medical specialties. 
Methodology: A cross-sectional questionnaire-based survey conducted among 249 clinicians focusing on the prevalence, symptoms, causes, clinical characteristics, management of GERD and the usage of its medications in clinical practice was conducted. 
Results: Obesity (39%) is the most common risk factor for GERD. About 42% respondents said the most commonly age group diagnosed with GERD was 40-55 years. Heart burn (56%) is the most common symptoms present in patients with GERD. Obesity (43%), diabetes mellitus (27%), dyslipidemia (11%), hypertension (16%) and asthma (3%) are the most common co-morbid conditions observed with GERD. Only 39% respondents said their patients complained of reflux symptoms being at both day and night, 29% said night time, 9% said both the above options and 3% said daytime. 41% respondents suggested PPI+ pro-kinetic agents as preferred therapy for GERD treatment. Pantoprazole (79%) is the most preferred PPIs in practice for GERD treatment. About 31% of respondents said that pantoprazole and domperidone cure rate for treatment of GERD is 70-80%. Pantoprazole 40mg twice daily (41%) is chosen by respondents as most effective therapy for refractory GERD when high dose of pantoprazole is required. PPI low dose (63%) is the most preferred therapy by respondents in GERD cases. 
Conclusion: Despite the challenges in managing GERD, clinicians generally felt confident in their ability to address this condition effectively. This survey highlights the importance of tailored management and the significance of evidence-based approaches to reduce GERD complications.

Pages: 01-06  |  113 Views  64 Downloads

International Journal of Gastroenterology Research
How to cite this article:
Manjula S and Krishna Kumar M. Prescription trends in the management of gastro-esophageal reflux disease (GERD) in India. Int. J. Gastroenterol. Res. 2024;6(1):01-06. DOI: 10.33545/26646439.2024.v6.i1a.3
International Journal of Gastroenterology Research

International Journal of Gastroenterology Research